Rotator Cuff Injuries: The Evolving Role of Tissue Engineering

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Rotator Cuff Injuries: The Evolving Role of Tissue Engineering

Aims: Rotator cuff injuries are a common injury associated with a combination of intrinsic and extrinsic causative factors. Although surgical reconstruction is a well established option, this is associated with variable re rupture rates. There is a growing body of interest in the potential tissue engineering in the management of rotator cuff injuries. This review aims to summarise the informati...

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INTRODUCTION Surgical repair of tendon, including rotator cuff injury, are common procedures, however structural failure of the surgical repair is a common complication of the surgery, and in some instances there is a need to replace injured tendon. There is therefore a recognized need to generate tissue engineered tendons for repair and replacement of damaged or diseased tendon (Derwin et al, ...

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Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering.

UNLABELLED The rotator cuff consists of several tendons and muscles that provide stability and force transmission in the shoulder joint. Whereas most rotator cuff tears are amenable to suture repair, the overall success rate of repair is low, and massive tears are prone to re-tear. Extracellular matrix (ECM) patches are used to augment suture repair, but they have limitations. Tissue-engineered...

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Diagnosis of tears in rotator-cuff-injuries.

Pathology of the rotator cuff is the cause of most common problems at the shoulder joint. Acute injuries are not as frequent as chronic cuff disease, but often they aggravate inflammatory or degenerative tendon alterations, even if they are of minor severity. Traumatic rotator cuff tears predominantly affect the supraspinatus tendon or the rotator interval. The subscapularis tendon is involved ...

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Rotator cuff injuries are a common source of shoulder pathology and result in an important decrease in quality of patient life. Given the frequency of these injuries, as well as the relatively poor result of surgical intervention, it is not surprising that new and innovative strategies like tissue engineering have become more appealing. Tissue-engineering strategies involve the use of cells and...

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ژورنال

عنوان ژورنال: British Journal of Medicine and Medical Research

سال: 2012

ISSN: 2231-0614

DOI: 10.9734/bjmmr/2012/565